Constant change, or anicca, is a central concept of Buddhism, one of the three marks of existence, along with dukkha (suffering) and anatta (non-self). The Gautama Buddha (c. 567- 487 BCE) taught that attaching to impermanence (e.g., your childhood goldfish, your adolescent puppy love, your undergraduate hairline, your spouse, your existence) ultimately results in sorrow. To escape the natural inclination to become attached to objects of desire, Gautama Buddha points out a pathway that enables one to transcend ego, i.e., to enter a state of anatta, in which one becomes not even zero but this  [ ].
The concept of constant change is inherent in quantum mechanics, cellular division, and, more obviously, in the shifting shapes of the clouds above. Everything is always in a state of flux. Not only did Eastern sages like Gautama come upon this concept of constant change, but also so did the Greek pre-Socratic philosopher — a contemporary of Gautama — Heraclitus, whose dates are c. 535 BCE – 475, BCE.
It’s easy to imagine Heraclitus’s most famous saying “No man ever steps into the same river twice” coming come from one of Gautama’s sermons. Unlike serene Gautama who suggested “a middle way,” Heraclitus, known as “the weeping philosopher,” was profoundly pessimistic. No doubt his pessimism contributed to what I hope are apocryphal accounts of his death.
According to Neanthes of Cyzicus, Heraclitus, suffering from dropsy, attempted to cure himself by covering his body with manure and lying out in the sun to dry, but he was made unrecognizable by the dung covering and was finally eaten by dogs. 
Not surprisingly, impermanence has been the theme of many a poet, and my main man WB Yeats is no exception. Take his masterpiece “Nineteen Hundred and Nineteen.”
Many ingenious lovely things are gone
That seemed sheer miracle to the multitude.
He offers examples of ancient art that has been lost:
[ . . .] There stood
Amid the ornamental bronze and stone
An ancient image made of olive wood –
And gone are Phidias’ famous ivories
And all the golden grasshoppers and bees.
Or as the latin poet Aaron Lipka puts it:
Vita brevis, ars longa,tamen non est sempiterna.
Yeats goes on to lament the end of the pax Victoria when “a great army [was] but a showy thing.” However, in 1919 the “days are dragon-ridden,” and “[t}he night can sweat with terror as before/ We pieced our thoughts into philosophy.”
He adds that he (or she) “who knows no work can stand [. . .] has but one comfort left: all triumph would/But break upon his ghostly solitude.”
He ends the first section of the poem with this stanza:
But is there any comfort to be found?
Man is in love and loves what vanishes,
What more is there to say? That country round
None dared admit, if such a thought were his,
Incendiary or bigot could be found
To burn that stump on the Acropolis,
Or break in bits the famous ivories
Or traffic in the grasshoppers or bees.
(Or, in the case of Hobby Lobby, traffic in stolen ancient Mesopotamian clay cuneiform tablets, perhaps looted by ISIS.)
Is what Yeats calls “ghostly solitude” anatta?”
Probably not. In Section 3, he refers to a Platonic theory of an afterlife. This theory holds that the greater a person’s accomplishments, the more likely those accomplishments will encumber her in her passage to the next world. Therefore, “if our works/Could vanish with our breath/That were a lucky death/For triumph can but mar our solitude.”
From the Cambridge Introduction to WB Yeats:
Before the poet can take comfort in his conclusions, it dawns on him that the evanescence of mortal triumphs is precisely what makes us love them. The fact that great works vanish does not make it easier to cast off our attachment to them. Indeed it makes it harder.
Today marks the 8th Sunday since my Judy died. The Buddhist ideal of total detachment, although wise, is better suited for one with a monastic temperament. If you are a husband or wife, a father or mother, a pet owner, a lover of Billie Holiday or the Marx Brothers, detachment is inexcusable. That doesn’t mean, however, you should embrace Heraclitus’ model and wallow in melancholy.
Weep when you must; party when you can.
Also, cynicism, though not ideal, can offer some satisfaction:
Come let us mock at the great
That had such burdens on the mind
And toiled so hard and late
To leave some monument behind,
Nor thought of the levelling wind.
Come let us mock at the wise;
With all those calendars whereon
They fixed old aching eyes,
They never saw how seasons run,
And now but gape at the sun.
Come let us mock at the good
That fancied goodness might be gay,
And sick of solitude
Might proclaim a holiday:
Wind shrieked — and where are they?
Mock mockers after that
That would not lift a hand maybe
To help good, wise or great
To bar that foul storm out, for we
Traffic in mockery.
 Insert “the sound of one hand clapping? The formula “form = emptiness; emptiness = form? The inexpressible mental concept of non-concept? Your original face before you were created?
 Janet Fairweather.“The Death of Heraclitus,” Greek, Roman, and Byzantine Studies.